Robert Morell, Ph.D., Director
Mission
The NIDCD Genomics and Computational Biology Core (GCBC) provides support for cutting edge high-throughput sequencing technologies to NIDCD and National Institute of Dental and Craniofacial Research (NIDCR) investigators on a collaborative basis. Our services include library preparation of investigator-supplied RNA or DNA samples, sequencing data generation, bioinformatic analyses, and publication-ready figure preparation. Intramural NIDCD and NIDCR investigators are charged for reagent costs of library preparation and sequencing only. The GCBC also archives the data and assists investigators in uploading the necessary data files to a suitable public repository, in compliance with NIH genomic data sharing policy.
Current projects in the GCBC include:
- Whole exome and whole genome sequencing
- Tissue-level RNA-seq
- Single-cell and single-nuclei RNA-seq
- Epigenomics (ChIP-seq, ATAC-seq, etc.)
- Custom projects
Sequencing platforms:
- Illumina HiSeq1500
- Illumina NextSeq500
- Illumina MiSeq
- Oxford Nanopore MinIon
- PacBio Sequel II
