Howard Hoffman, M.A.

OFFICE OF THE DIRECTOR

BG 6001 EXECUTIVE BLVD NSC RM 8325 6001 EXECUTIVE BLVD ROCKVILLE MD 20852

MSC:

9670

Phone:

+1 301 402 1843

Fax:

+1 301 402 0390

Email:

hoffmanh@mail.nih.gov

Chief, Epidemiology, Statistics, and Population Sciences Section

Howard J. Hoffman is the chief of the NIDCD Epidemiology, Statistics, and Population Sciences Section. This research program focuses on prevalence, incidence, risk factors, and preventive interventions for disorders of hearing, balance, taste, smell, voice, speech, and language. Hoffman is the NIDCD project officer for the National Health and Nutrition Examination Survey (NHANES) hearing, balance, and chemosensory examination components and other NIDCD epidemiologic studies in the U.S. and abroad, including the National Health Interview Survey (NHIS) 2002, 2007, 2014, and 2016 Communication Disorders Supplements. He is NIDCD co-lead for the Healthy People 2030 objective on Sensory or Communication Disorders.

Scientific Program Area:

Epidemiology, Statistics, and Population Sciences

Scientific Areas:

Epidemiology, Statistics, and Population Sciences

Selected Publications

Trpchevska N, Freidin MB, Broer L, Oosterloo BC, Yao S, Zhou Y, Vona B, Bishop C, Bizaki-Vallaskangas A, Canlon B, Castellana F, Chasman DI, Cherny S, Christensen K, Concas MP, Correa A, Elkon R; Estonian Biobank Research Team, Mengel-From J, Gao Y, Giersch ABS, Girotto G, Gudjonsson A, Gudnason V, Heard-Costa NL, Hertzano R, Hjelmborg JVB, Hjerling-Leffler J, Hoffman HJ, Kaprio J, Kettunen J, Krebs K, Kähler AK, Lallemend F, Launer LJ, Lee IM, Leonard H, Li CM, Lowenheim H, Magnusson PKE, van Meurs J, Milani L, Morton CC, Mäkitie A, Nalls MA, Nardone GG, Nygaard M, Palviainen T, Pratt S, Quaranta N, Rämö J, Saarentaus E, Sardone R, Satizabal Barrera CL, Schweinfurth JM, Seshadri S, Shiroma E, Shulman E, Simonsick E, Spankovich C, Tropitzsch A, Lauschke VM, Sullivan PF, Goedegebure A, Cederroth CR, Williams FMK, Nagtegaal AP. Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss. Am J Hum Genet. 2022 May 12:S0002-9297(22)00158-6. doi: 10.1016/j.ajhg.2022.04.010. Epub ahead of print. PMID: 35580588.
Niemczak CE, Cox C, Grigoryan G, Springer G, Fellows AM, Torre P 3rd, Hoffman HJ, Buckey JC, Plankey MW. Gap detection responses modelled using the Hill equation in adults with well-controlled HIV. Int J Audiol. 2022 May 6:1-10. doi: 10.1080/14992027.2022.2068083. Online ahead of print. PMID: 35521916.
Rawal S, Duffy VB, Berube L, Hayes JE, Kant AK, Li CM, Graubard BI, Hoffman HJ. Self-reported olfactory dysfunction and diet quality: Findings from the 2011-2014 National Health and Nutrition Examination Survey (NHANES). Nutrients. 2021 Dec 20;13(12):4561. doi: 10.3390/nu13124561. PMID: 34960113.
Odendaal H, Dukes KA, Elliott AJ, Willinger M, Sullivan LM, Tripp T, Groenewald C, Myers MM, Fifer WP, Angal J, Boyd TK, Burd L, Cotton JB, Folkerth RD, Hankins G, Haynes RL, Hoffman HJ, Jacobs PK, Petersen J, Pini N, Randall BB, Roberts DJ, Robinson F, Sens MA, Van Eerden P, Wright C, Holm IA, Kinney HC; Prenatal Alcohol in SIDS and Stillbirth (PASS) Network. Association of prenatal exposure to maternal drinking and smoking with the risk of stillbirth. JAMA Netw Open. 2021 Aug 2;4(8):e2121726. doi: 10.1001/jamanetworkopen.2021.21726. PMID: 34424306.
Berube L, Duffy VB, Hayes JE, Hoffman HJ, Rawal S. Associations between chronic cigarette smoking and taste function: Results from the 2013-2014 national health and nutrition examination survey. Physiol Behav. 2021 Oct 15;240:113554. doi: 10.1016/j.physbeh.2021.113554. Epub 2021 Aug 8. PMID: 34375623.
Sininger YS, Condon CG, Gimenez LA, Shuffrey LC, Myers MM, Elliott AJ, Thai T, Nugent JD, Pini N, Sania A, Odendaal HJ, Angal J, Tobacco D, Hoffman HJ, Simmons DD, Fifer WP. Prenatal exposure to tobacco and alcohol alters development of the neonatal auditory system. Dev Neurosci. 2021;43(6):358-375. doi: 10.1159/000518130. Epub 2021 Jul 19. PMID: 34348289.
GBD 2019 Hearing Loss Collaborators. Hearing loss prevalence and years lived with disability, 1990-2019: findings from the Global Burden of Disease Study 2019. Lancet. 2021 Mar 13;397(10278):996-1009. doi: 10.1016/S0140-6736(21)00516-X. PMID: 33714390.
Pichert MD, Plankey MW, Springer G, Cox C, Hoffman HJ, Cohen HS. Vestibular and oculomotor abnormalities among HIV-infected and HIV-uninfected men and women: A pilot study. J Vestib Res. 2020;30(5):329-334. doi: 10.3233/VES-200707. PMID: 32741798.
Elliott AJ, Kinney HC, Haynes RL, Dempers JD, Wright C, Fifer WP, Angal J, Boyd TK, Burd L, Burger E, Folkerth RD, Groenewald C, Hankins G, Hereld D, Hoffman HJ, Holm IA, Myers MM, Nelsen LL, Odendaal HJ, Petersen J, Randall BB, Roberts DJ, Robinson F, Schubert P, Sens MA, Sullivan LM, Tripp T, Van Eerden P, Wadee S, Willinger M, Zaharie D, Dukes KA. Concurrent prenatal drinking and smoking increases risk for SIDS: Safe Passage Study report. EClinicalMedicine. 2020 Jan 20;19:100247. doi: 10.1016/j.eclinm.2019.100247. eCollection 2020 Feb. PMID: 32140668.
Torre P 3rd, Russell JS, Smith R, Hoffman HJ, Lee S, Williams PL, Yao TJ; Pediatric HIV/AIDS Cohort Study (PHACS). Words-in-Noise test performance in young adults perinatally HIV infected and exposed, uninfected. Am J Audiol. 2020 Mar 5;29(1):68-78. doi: 10.1044/2019_AJA-19-00042. Epub 2020 Jan 31. PMID: 32004075.
Bigelow RT, Semenov YR, Hoffman HJ, Agrawal Y. Association between vertigo, cognitive and psychiatric conditions in US children: 2012 National Health Interview Survey. Int J Pediatr Otorhinolaryngol. 2020 Mar;130:109802. doi: 10.1016/j.ijporl.2019.109802. Epub 2019 Nov 28. PMID: 31809971.
Purswani MU, Russell JS, Dietrich M, Malee K, Spector SA, Williams PL, Frederick T, Burchett S, Redmond S, Hoffman HJ, Torre P 3rd, Lee S, Rice ML, Yao TJ; Pediatric HIV/AIDS Cohort Study. Birth prevalence of congenital cytomegalovirus infection in HIV-exposed uninfected children in the era of combination antiretroviral therapy. J Pediatr. 2020 Jan;216:82-87.e2. doi: 10.1016/j.jpeds.2019.09.025. Epub 2019 Oct 23. PMID: 31668479.
Olusanya BO, Davis AC, Hoffman HJ. Hearing loss grades and the International classification of functioning, disability and health. Bull World Health Organ. 2019 Oct 1;97(10):725-728. doi: 10.2471/BLT.19.230367. Epub 2019 Sep 3. PMID: 31656340.
Olusanya BO, Davis AC, Hoffman HJ. Hearing loss: rising prevalence and impact. Bull World Health Organ. 2019 Oct 1;97(10):646-646A. doi: 10.2471/BLT.19.224683. PMID: 31656325.
Nagtegaal AP, Broer L, Zilhao NR, Jakobsdottir J, Bishop CE, Brumat M, Christiansen MW, Cocca M, Gao Y, Heard-Costa NL, Evans DS, Pankratz N, Pratt SR, Price TR, Spankovich C, Stimson MR, Valle K, Vuckovic D, Wells H, Eiriksdottir G, Fransen E, Ikram MA, Li CM, Longstreth WT Jr, Steves C, Van Camp G, Correa A, Cruickshanks KJ, Gasparini P, Girotto G, Kaplan RC, Nalls M, Schweinfurth JM, Seshadri S, Sotoodehnia N, Tranah GJ, Uitterlinden AG, Wilson JG, Gudnason V, Hoffman HJ, Williams FMK, Goedegebure A. Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. Sci Rep. 2019 Oct 23;9(1):15192. doi: 10.1038/s41598-019-51630-x. PMID: 31645637.
Gallo S, Byham-Gray L, Duffy VB, Hoffman HJ, Hayes JE, Rawal S. Associations of olfactory dysfunction with anthropometric and cardiometabolic measures: Findings from the 2013-2014 national health and nutrition examination survey (NHANES). Physiol Behav. 2020 Mar 1;215:112702. doi: 10.1016/j.physbeh.2019.112702. Epub 2019 Oct 17. PMID: 31629766.
Hillman LS, Day LS, Hoffman HJ, Stockbauer JW. Poorer outcomes of all low birth weight groups at age 10: Missouri statewide case-control study. Early Hum Dev. 2019 Sep;136:60-69. doi: 10.1016/j.earlhumdev.2019.05.006. Epub 2019 Aug 1. PMID: 31377564.
GBD 2016 Traumatic Brain Injury and Spinal Cord Injury Collaborators. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease study 2016. Lancet Neurol. 2019 Jan;18(1):56-87. doi: 10.1016/S1474-4422(18)30415-0. Epub 2018 Nov 26. PMID: 30497965.
Hoffman HJ, Dobie RA, Losonczy KG, Themann CL, Flamme GA. Kids nowadays hear better than we did: Declining prevalence of hearing loss in US Youth, 1966–2010. Laryngoscope. 2018 Oct 5. doi: 10.1002/lary.27419. [Epub ahead of print]
Hoffman HJ. Childhood hearing loss and established risk factors: What is the contribution of tobacco exposure prenatally or after birth? Paediatr Perinat Epidemiol. 2018 Sep; 32(5): 439–441.
Li CM, Zhao G, Hoffman HJ, Town M, Themann CL. Hearing disability prevalence and risk factors in two recent national surveys. Am J Prev Med. 2018 Sep; 55(3): 326–335.
Sininger YS, Condon CG, Hoffman HJ, Elliott AJ, Odendaal HL, Burd LL, Myers MM, Fifer WP; PASS Network. Transient otoacoustic emissions and auditory brainstem responses in low-risk cohort of newborn and one-month-old infants: Assessment of infant auditory system physiology in the Prenatal Alcohol in SIDS and Stillbirth Network Safe Passage Study. J Am Acad Audiol. 2018 Sep; 29(8): 748–763.
Black LI, Zammitti EP, Hoffman HJ, Li CM. Parental report of significant head injuries in children aged 3-17 years: United States, 2016. NCHS Data Brief. 2018 Feb; No. 302, pp 1–8.
Hoffman HJ, Dobie RA, Losonczy KG, Themann CL, Flamme GA. Declining prevalence of hearing loss in US adults aged 20 to 69 years. JAMA Otolaryngol Head Neck Surg. 2017 Mar 16; 143(3): 274-285.
Carroll YI, Eichwald J, Scinicariello F, Hoffman HJ, Deitchman S, Radke MS, Themann CL, Breysse P. Vital Signs: Noise-induced hearing loss among adults - United States 2011–2012. Mortal Morbid Weekly Rep. 2017 Feb 10; 66(5): 139-144.
Simon AE, Boss EF, Zelaya CE, Hoffman HJ. Racial and ethnic differences in receipt of pressure equalization tubes among US children, 2014. Acad Pediatr. 2017 Jan-Feb; 17(1): 88-94.
Redmond SM, Yao TJ, Russell JS, Rice ML, Hoffman HJ, Siberry GK, Frederick T, Purswami M, Williams PL; Pediatric HIV/AIDS Cohort Study. Longitudinal evaluation of language impairment in youth with perinatally acquired human immunodeficiency virus (HIV) and youth with perinatal HIV exposure. J Pediatric Infect Dis Soc. 2016 Dec; 5(suppl 1): S33-S40.
Bainbridge KE, Roy N, Losonczy KG, Hoffman HJ, Cohen SM. Voice disorders and associated risk markers among young adults in the United States. Laryngoscope. 2016 Dec 23; E1-E7.
Lie A, Engdahl B, Hoffman HJ, Li C-M, Tambs K. Occupational noise exposure, hearing loss, and notched audiograms in the HUNT Nord-Trøndelag hearing loss study, 1996–1998. Laryngoscope. 2016 Oct 3; E1-E9.
Hoffman HJ, Rawal S, Li CM, Duffy VB. New chemosensory component in the U.S. National Health and Nutrition Examination Survey (NHANES): first-year results for measured olfactory dysfunction. Rev Endocr Metab Disord. 2016 Jun; 17(2): 221-240.

Last Updated Date:

February 19, 2025