July 22–23, 2008
Hyatt Regency, Bethesda, Maryland
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Agenda
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Tuesday July 22, 2008 |
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| 7:45–8:30 a.m. | Continental breakfast | |
| 8:30–8:35 a.m. | Welcome |
Judith Cooper, Ph.D. |
| 8:35–8:45 a.m. | Introductions and workshop overview | Workshop Chair - Dennis Trune, Ph.D., Oregon Health & Science University |
| Background | ||
| 8:45–9:15 a.m. | Definitions, etiology, cardinal features, diagnosis: What constitutes autoimmune hearing loss?
Q & A |
Lawrence Lustig, M.D., University of California at San Francisco |
| 9:15–9:45 a.m. | Innate immunity of the inner ear: Roles of the endolymphatic sac and spiral ligament cells
Q & A |
David Lim, M.D., House Ear Institute |
| 9:45–10:15 a.m. | Discussion | |
| 10:15–10:30 a.m. | Break | |
| Cell and Antibody Immune Responses in the Ear | ||
| 10:30–11:00 a.m. | What evidence is there for cell mediated immune responses in the ear?
Q & A |
Vincent Tuohy, Ph.D., Case Western Reserve |
| 11:00–11:30 a.m. | Antibody mediated immune processes
Q & A |
Pavan Kommareddi, Ph.D., University of Michigan |
| 11:30–noon | Discussion | |
| Noon–1:30 p.m. | Lunch (on your own) | |
| Systemic Immune Responses in the Ear: Alternative Paradigms: Sites of the Immune Response in the Ear | ||
| 1:30–2:00 p.m. | React-Respond-Repair-Restore: Is the ear directly affected by immune disease or the body's healing reaction to it?
Q & A |
Dennis Trune, Ph.D., Oregon Health and Science University |
| 2:00–2:30 p.m. | Systemic inflammatory processes and biomarkers
Q & A |
Andrea Vambutas, M.D., Albert Einstein College of Medicine, Long Island Jewish Medical Center |
| 2:30–3:00 p.m. | Discussion | |
| 3:00–3:15 p.m. | Break | |
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Infectious Agents |
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| 3:15–3:45 p.m. | How can systemic infections cause hearing loss? The case of CMV
Q & A |
Mark Schleiss, M.D., University of Minnesota |
| 3:45–4:15 p.m. | Discussion |
Mark Schleiss, M.D., University of Minnesota |
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Genetic Strategies |
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| 4:15–4:45 p.m. | Genetics and susceptibility loci in immune mediated hearing loss: Getting the phenotype right. Is there evidence of a heritable component? |
Rick Friedman, M.D., Ph.D., House Ear Institute |
| 4:45–5:15 p.m. | Discussion
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Wednesday July 23, 2008 |
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|---|---|---|
| 8:00–8:30 a.m. |
Continental breakfast |
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| View from Outside Otolaryngology: Lessons to be Learned from Other Autoimmune Disorders | ||
| 8:30–9:00 a.m. | Successful strategies and lessons learned from other autoimmune diseases |
Noel Rose, M.D., Johns Hopkins University |
| 9:00–9:30 a.m. | Basic science to clinical translation: What is needed from the industry perspective? |
Vijay Kumar Ph.D., IMMCO Diagnostics, Inc., Buffalo, N.Y. |
| 9:30–10:00 a.m. | Discussion | |
| 10:00–10:15 a.m. | Break | |
| 10:15–11:45 a.m. | Identify research gaps and research needs; establish priorities | |
| Noon | Adjourn | |
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