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A Mouse with Golden Ears

What a Mouse with ‘Golden Ears’ can Tell Us About Older Brains

In recent research published in the Neurobiology of Aging, NIDCD-supported scientists have created a mouse model that is comparable to an older adult who has the ears of a healthy 20-year-old but the brain of that 20-year-old’s great-grandmother. They created the model when they crossed two mouse strains commonly used to study age-related hearing loss. Using technologies that are commonly used to screen newborns for hearing loss, the researchers found that the offspring of this cross had significantly better hearing than either of the parents, but their brains had difficulty compensating for sound in background noise. Read more on the NIDCD Web site, or read the abstract on Pub Med.

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